魏登帅博士，副教授、硕士生导师

中国科协青年人才托举工程入选者、山东省泰山学者青年专家。

学习经历：

2019.9—2022.6，中国科学院大学，博士，导师：肖海华研究员；

2016.9—2019.6，北京工业大学，硕士，导师：胡利明教授；

2012.9—2016.6，青岛科技大学，本科。

工作简介：

2022年6月毕业于中国科学院化学研究所，获理学博士学位，同年加入青岛大学药学院药剂学系。研究内容为药物和基因的靶向递送。研究结果发表在J. Am. Chem. Soc., Angew. Chem., ACS Nano, Nano Today, JCR,AHM,Bioorganic Chemistry等国际期刊，获批国家发明专利5项，指导大学生创新创业计划多项。

研究方向：

1.新型药物和基因递送体系的设计和开发；

2.活体荧光检测体系的设计和开发；

代表性论文：

Wei, D.; Fan, J.; Yan, J.;et al.,Nuclear-Targeting Lipid Pt^IVProdrug Amphiphile Cooperates with siRNA for Enhanced Cancer Immunochemotherapy by Amplifying Pt-DNA Adducts and Reducing Phosphatidylserine Exposure,J. Am. Chem. Soc. 2024, 146, 1, 1185.

Wei, D.; Huang, Y.; Wang B.;et al.Photo-Reduction with NIR Light of Nucleus Targeting Pt^IVNanoparticles for Combined Tumor-Targeted Chemotherapy and Photodynamic Immunotherapy.Angew. Chem. Int. Ed. 2022, e202201486.

Wei, D.; Sun, Y.; Zhu, H.;et al.,Stimuli-Responsive Polymer-Based Nanosystems for Cancer Theranostics,ACS Nano2023, 17, 23, 23223.

Wei, D.; Chen, Y.; Huang, Y.;et al.,NIR-Light-Triggered Cascade Dual-Targeting Core-Shell Nanoparticles for Optimized Photodynamic Therapy and Immunotherapy.Nano Today2021, 41, 101288.

Wei, D.; Yu, Y.;Huang, Y.;et al.,A Near-Infrared-II Polymer with Tandem Fluorophores Demonstrates Superior Biodegradability for Simultaneous Drug Tracking and Treatment Efficacy Feedback.ACS Nano2021, 15, 5428.

Wei, D.; Yu, Y.; Zhang, X.;et al.,Breaking the Intracellular Redox Balance with Diselenium Nanoparticles for Maximizing Chemotherapy Efficacy on Patient-Derived Xenograft Models.ACS Nano, 2020, 14, 16984.

Wei, D.; Yan J.; Cao Z.;et al.,Nucleus-targeting Oxaplatin(IV) Prodrug Amphiphile for Enhanced Chemotherapy and Immunotherapy,J. Control. Release.2024, 373, 216.

联系电话：18810938219

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